Stem cells are mother cells that have the potential to become
any type of cell in the body. One of the main characteristics of stem cells is
their ability to self-renew or multiply while maintaining the potential to
develop into other types of cells. Stem cells can become cells of the blood,
heart, bones, skin, muscles, brain etc. There are different sources of
stem cells but all types of stem cells have the same capacity to develop into
multiple types of cells.
Types
of stem cells
Pluripotent Stem Cells (PS cells)
These
possess the capacity to divide for long periods and retain their ability to
make all cell types within the organism. The best known type of pluripotent
stem cell is the one present in embryos that helps babies grow within the womb.
These are termed embryonic stem cells. These cells form at
the blastocyst stage of development. A blastocyst is a hollow ball of cells
that is smaller than a pinhead. The embryonic stem cells lie within this ball
of cells. Recent research has enabled scientists to derive pluripotent cells
from adult human skin cells. These are termed induced pluripotent stem cells or
iPS cells.
Fetal stem cells
These
are obtained from tissues of a developing human fetus. These cells have some
characteristics of the tissues they are taken from. For example, those taken
from fetal muscles can make only muscle cells. These are also called progenitor
cells.
Adult stem cells
These
are obtained from some tissues of the adult body. The most commonly used
example is the bone marrow. Bone marrow is a rich source
of stem cells that can be used to treat some blood diseases and cancers.
Discovery
of stem cells
Scientists
first studied the potential of stem cells in mouse embryos over two decades
ago. Over years of research they discovered the properties of these stem cells
in 1998. They found methods to isolate stem cells from human embryos and grow
the cells in the laboratory.
Early
studies utilized embryos created for infertility purposes through in vitro
fertilization procedures and when they were no longer needed for that purpose.
The use required voluntary donation of the embryos by the owners.
Potential
for use
Stem
cell research is improving by leaps and bounds. These may soon become the basis
for treating diseases such as Parkinson's disease, diabetes, heart failure, cerebral palsy, heart disease and host of
other chronic ailments.
Stem
cells may also be used for screening new drugs and toxins and understanding
birth defects without subjecting human volunteers to the toxins and drugs.
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